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Fat layers and muscles
Fat-reduction treatments target the subcutaneous fat between the skin and the muscle. Muscle devices target the muscle under that fat. Fat inside the abdomen, deep to the muscles, is not a target.
Layer by layer
Scarpa fascia separates the superficial fat from a deeper fat layer. On the same CT scans, the deep layer averaged 14 mm at the mid abdomen and 5 mm in the lower abdomen. truSculpt biopsies showed fat cell death from just under the dermis to about 1.5 cm below the skin.[1][2]
Fat deep to the abdominal muscles lies around the organs. Applicators work from the skin surface, and ASPS lists fat inside the abdomen as a reason not to have laser lipolysis.[1]
Kybella is injected into the pre-platysmal fat, the fat between the dermis and the platysma muscle. Injections stay away from the platysma, the marginal mandibular nerve, salivary glands and lymph nodes. CoolSculpting was cleared for the submental area in 2015.[1][2]
HIFEM devices contract the abdominal muscles. In a 22-patient MRI study, rectus abdominis thickness rose 15.4% and the gap between the two rectus muscles narrowed 10.4% at 2 months. A systematic review states early muscle gains likely reflect swelling after exercise.[1][2]