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History

History of laser skin resurfacing

From selective photothermolysis in 1983 to fractional and hybrid lasers: the steps that changed the treatment.

Timeline

Laser Skin Resurfacing timeline

1917

Stimulated emission described

Einstein described stimulated emission, the principle behind the laser. Dermatologists, Leon Goldman foremost, later took part in developing medical lasers.[1]

1983

Selective photothermolysis

Brief pulses of a wavelength absorbed by one target damaged that target and spared nearby tissue. Pulses of 577 nm hit small vessels and 351 nm hit pigment granules.[1]

1989

Erbium laser ablates skin

The 2,940 nm erbium:YAG laser made clean, precise skin lesions with minimal injury nearby, in excised human skin and pig skin.[1]

1991

UltraPulse CO2 laser cleared

FDA cleared the UltraPulse carbon dioxide surgical laser on August 13, 1991.[1]

1993

CO2 resurfacing of the face

CO2 laser resurfacing of photoaged facial skin began in late 1993. Patients treated from 1993 to 1996 kept their wrinkle improvement an average of 24 months later.[1]

1996

Pulsed CO2 results published

High-energy pulsed CO2 treatment of 111 perioral and periorbital areas cut wrinkle scores by more than 2 points on a 9-point scale and tightened loose skin.[1]

1998

Complications in 500 patients

A review of 500 CO2 patients found redness in all, darkening in 37%, herpes simplex in 7.4%, and scarring or lightening in under 1%.[1]

2000

IPL photorejuvenation

Serial full-face intense pulsed light treatments improved sun damage in more than 90% of 49 people with minimal downtime.[1]

2003

First fractional laser and BBL cleared

FDA cleared the Reliant Laser System on November 10, 2003, and the Sciton Profile BBL on November 13, 2003.[1][2]

2004

Fractional photothermolysis

A 1.5 micron laser placed microscopic columns of heat in the skin with healthy skin between them. The surface healed within 1 day.[1]

2007

Ablative fractional CO2

A 30 W fractional CO2 prototype made ablative columns in human skin, about 350 microns wide and 1 mm deep.[1]

2011

Low-power fractional diode cleared

FDA cleared Clear + Brilliant on May 3, 2011, at preset energies at the low end of the Fraxel IV SR range.[1]

2014

Picosecond lens array cleared

FDA cleared PicoSure with the Focus array for acne scars and wrinkles in skin types I to IV on September 22, 2014.[1][2]

2018

Hybrid fractional laser trial

A multi-center trial tested a laser that pairs 1,470 nm coagulation with 2,940 nm ablation in one treatment.[1]

People

The researchers behind the methods

Their papers set the methods in use today.

1983, 2004

R. R. Anderson

Co-author of selective photothermolysis (1983) and of the first fractional photothermolysis report (2004).[1][2]

1983

J. A. Parrish

Co-author of the 1983 selective photothermolysis paper in Science.[1]

2004

D. Manstein

First author of the 2004 fractional photothermolysis paper.[1]

1989

R. Kaufmann and R. Hibst

Showed in 1989 that the erbium:YAG laser ablates skin with minimal nearby injury.[1]

1996-1999

R. E. Fitzpatrick

Published pulsed CO2 resurfacing results in 1996 and long-term follow-up in 1999.[1][2]

1996-1999

M. P. Goldman

Co-author of the 1996 pulsed CO2 study and the 1999 long-term follow-up.[1][2]

1998-2008

T. S. Alster

Reported complications in 500 CO2 patients (1998) and in 961 fractional 1,550 nm treatments (2008).[1][2]

2007

B. M. Hantash

First author of the first study of an ablative fractional CO2 device (2007).[1]

2000-2013

P. H. Bitter

Published serial full-face IPL photorejuvenation in 2000; co-author of the 2013 BBL gene-expression study.[1][2]

2015-2016

J. A. Brauer and R. G. Geronemus

Published the picosecond laser with diffractive lens array for acne scars (2015) and its safety in skin types IV to VI (2016).[1][2]