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Gluteal layers
The buttock has six layers from outside in. Fat is placed only above the deep fascia; the large gluteal veins lie under the gluteus maximus, about 56 mm deep.
Outside to inside
The skin is tethered by osseocutaneous and fasciocutaneous ligaments. In 10 cadaver hemibuttocks, these ligaments could deflect a cannula deeper than intended unless they were released.[1]
The outer fat layer holds the smallest vessels in the buttock. In 20 cadaver dissections the subcutaneous plane held about 25 vessels, with arteries of 0.9 mm and veins of 1.05 mm.[1]
A 2023 cadaver study found 7 deep subcutaneous fat compartments: 3 medial, 1 central and 3 lateral. Each keeps injected fat apart from the others above the muscle fascia, and surgeons can fill them selectively under ultrasound.[1]
The superior and inferior gluteal veins run just under the gluteus maximus, on average 56 mm deep and about 6 mm wide with the patient prone. The MRI study found no safe zone in or under the muscle. The 2018 task force reported fat in the gluteal muscle in every BBL death examined at autopsy.[1][2]